Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13831055 | 0.78 | — | — | |
| SCHEMBL5539578 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL4405692 | 0.76 | — | — | |
| SCHEMBL4407247 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HTR1AHTR2C | |
| SCHEMBL6473514 | 0.72 | ALDH1A1 (0.38) | ALDH1A1HTR1AHTR2C | |
| SCHEMBL6474091 | 0.71 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HTR1AHTR2C | |
| SCHEMBL10672830 | 0.70 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL95968 | 0.69 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL4409273 | 0.69 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4788963 | 0.69 | ALDH1A1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358327-A | A DIISOCYANATE-CURED BINDER OF ENDCAPPED POLYOXYPROPYLENE GLYCOL AND A DI/2-HYDROXYETHYL)TETRAZOLE; LOW TEMPERATURE; INFLATABLE DEVICES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1982-11-09 | — | — | US | claimed |
| US-4358327-A | A DIISOCYANATE-CURED BINDER OF ENDCAPPED POLYOXYPROPYLENE GLYCOL AND A DI/2-HYDROXYETHYL)TETRAZOLE; LOW TEMPERATURE; INFLATABLE DEVICES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1982-11-09 | — | — | US | disclosed |