SCHEMBL11286557

SCHEMBL11286557

S=C(S)NCCOCCNC(=S)S

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP2C9 P11712 2/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
CYP2C19 P33261 1/20 0.52
LMNA P02545 2/20 0.39
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11294492 0.97 HSD17B10 (0.50) HSD17B10ALDH1A1CYP2C9HPGDALOX15
SCHEMBL24393289 0.91 TSHR (0.46) HSD17B10ALDH1A1CYP2C9HPGDALOX15
SCHEMBL21215054 0.87 ALDH1A1 (0.41) HSD17B10ALDH1A1CYP2C9HPGDALOX15
SCHEMBL7585615 0.87 ALDH1A1 (0.41) HSD17B10ALDH1A1CYP2C9HPGDALOX15
SCHEMBL7135294 0.87 ALDH1A1 (0.41) HSD17B10ALDH1A1CYP2C9HPGDALOX15
SCHEMBL1673621 0.85
SCHEMBL9511778 0.85
SCHEMBL17266167 0.79 HSD17B10 (0.48) HSD17B10ALDH1A1CYP2C9HPGDALOX15
SCHEMBL9509500 0.79
SCHEMBL83488 0.78 HSD17B10 (0.67) HSD17B10ALDH1A1CYP2C9HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0010336-B1 NOVEL BIS(DITHIOCARBAMATE) SALTS AND COMPLEXES AND METHODS AND COMPOSITIONS FOR CONTROLLING FUNGI THE DOW CHEMICAL COMPANY (US) 1982-05-19 EP disclosed
US-4243675-A FUNGICIDES THE DOW CHEMICAL COMPANY (US) 1981-01-06 US disclosed
US-4211784-A FUNGICIDES THE DOW CHEMICAL COMPANY (US) 1980-07-08 US disclosed
US-4203999-A FUNGICIDES THE DOW CHEMICAL COMPANY (US) 1980-05-20 US disclosed
EP-0010336-A1 Novel bis(dithiocarbamate) salts and complexes and methods and compositions for controlling fungi THE DOW CHEMICAL COMPANY (US) 1980-04-30 EP disclosed