Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | PARP1 | P09874 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13901617 | 0.91 | HPGD (0.61) | HPGDMAPK1KDM4EHSD17B10PARP1 | |
| Hydrochloric Acid SCHEMBL1720180 | 0.90 | HPGD (0.60) | HPGDMAPK1KDM4EHSD17B10PARP1 | |
| SCHEMBL10227998 | 0.86 | PARP1 (0.55) | HPGDMAPK1KDM4EHSD17B10PARP1 | |
| SCHEMBL10228002 | 0.85 | PARP1 (0.54) | HPGDMAPK1KDM4EHSD17B10PARP1 | |
| Hydrochloric Acid SCHEMBL1719955 | 0.85 | PARP1 (0.54) | HPGDMAPK1KDM4EHSD17B10PARP1 | |
| SCHEMBL1720914 | 0.84 | KDM4E (0.56) | HPGDMAPK1KDM4EHSD17B10PARP1 | |
| SCHEMBL13901616 | 0.84 | HPGD (0.52) | HPGDMAPK1KDM4EHSD17B10PARP1 | |
| Hydrochloric Acid SCHEMBL1720581 | 0.84 | PARP1 (0.53) | HPGDMAPK1KDM4EHSD17B10PARP1 | |
| Hydrochloric Acid SCHEMBL4069640 | 0.83 | KDM4E (0.56) | HPGDMAPK1KDM4EHSD17B10PARP1 | |
| Hydrochloric Acid SCHEMBL1719788 | 0.83 | HPGD (0.51) | HPGDMAPK1KDM4EHSD17B10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113731-A | PHOTOGRAPHIC EMULSION STABILIZERS | GRUPPO LEPETIT S.P.A. (IT) | 1978-09-12 | — | — | US | claimed |
| EP-0005745-B1 | PYRAZOLO (3,4-C) AND THIAZOLO (5,4-C) ISOQUINOLINES, METHODS FOR PREPARING THEM, THESE COMPOUNDS FOR USE AS ANTIINFLAMMATORY, CNS-DEPRESSANT AND ANTI-ANXIETY AGENTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | GRUPPO LEPETIT S.P.A. (IT) | 1982-07-14 | — | — | EP | disclosed |
| US-4232017-A | CNS DEPRESSANTS; TRANQUILIZERS | GRUPPO LEPETIT S.P.A. (IT) | 1980-11-04 | — | — | US | disclosed |
| EP-0005745-A1 | Pyrazolo (3,4-c) and thiazolo (5,4-c) isoquinolines, methods for preparing them, these compounds for use as antiinflammatory, CNS-depressant and anti-anxiety agents and pharmaceutical compositions thereof | GRUPPO LEPETIT S.P.A. (IT) | 1979-12-12 | — | — | EP | disclosed |
| US-4113731-A | PHOTOGRAPHIC EMULSION STABILIZERS | GRUPPO LEPETIT S.P.A. (IT) | 1978-09-12 | — | — | US | disclosed |