Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2699905 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPTMCL1ATMSMN1; SMN2 | |
| SCHEMBL23228841 | 0.69 | CMA1 (0.45) | ALDH1A1MAPTATMMAOBALOX5 | |
| SCHEMBL18112585 | 0.69 | CMA1 (0.45) | ALDH1A1MAPTATMMAOBALOX5 | |
| SCHEMBL86407 | 0.67 | ATM (0.56) | ALDH1A1MAPTMCL1ATMMAOA | |
| SCHEMBL8099032 | 0.65 | TTR (0.48) | ALDH1A1MAPTCYP19A1MAOAMAOB | |
| Hno SCHEMBL6475533 | 0.64 | ATM (0.54) | ALDH1A1MAPTMCL1ATMMAOA | |
| SCHEMBL7535089 | 0.64 | CYP1A2 (0.55) | CYP19A1MAOAMAOBSMN1; SMN2TRPV1 | |
| SCHEMBL28779440 | 0.64 | CYP1A2 (0.55) | CYP19A1MAOAMAOBSMN1; SMN2TRPV1 | |
| (Z)-1,2-Diphenylethene SCHEMBL28291545 | 0.63 | MAOB (0.65) | ALDH1A1CYP19A1MAOAMAOBTTR | |
| (Z)-1,2-Diphenylethene SCHEMBL443 | 0.63 | MAOB (0.73) | ALDH1A1CYP19A1MAOAMAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4312802-A | POLYSTYRENE MATRIX WITH DISPERSION OF CROSSLINKED POLYBUTADIENE PARTICLES; IMPACT STRENGTH, CHEMICAL RESISTANCE | UNITED STATES STEEL CORPORATION (US) | 1982-01-26 | — | — | US | disclosed |
| US-4212789-A | Process for preparing high impact polystyrenes | UNITED STATES STEEL CORPORATION (US) | 1980-07-15 | — | — | US | disclosed |