Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576244 | 0.82 | MAPT (0.41) | ALDH1A1TSHRMAPTPOLBCYP3A4 | |
| Perchlorate SCHEMBL10912713 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRNAPRTDAOMAPT | |
| SCHEMBL14628782 | 0.74 | ALDH1A1 (0.40) | ALDH1A1TSHRNAPRTDAOALOX15 | |
| SCHEMBL11291960 | 0.74 | MAPT (0.38) | ALDH1A1TSHRNAPRTDAOALOX15 | |
| SCHEMBL1489277 | 0.73 | KDM4E (0.44) | ALDH1A1TSHRNAPRTDAOALOX15 | |
| SCHEMBL13113036 | 0.73 | HDAC8 (0.43) | ALDH1A1TSHRNAPRTDAOALOX15 | |
| SCHEMBL29475148 | 0.73 | KDM4E (0.44) | ALDH1A1TSHRNAPRTDAOALOX15 | |
| SCHEMBL123490 | 0.71 | ALDH1A1 (0.37) | ALDH1A1TSHRNAPRTDAOALOX15 | |
| Hydrochloric Acid SCHEMBL11768005 | 0.71 | HDAC8 (0.41) | ALDH1A1TSHRNAPRTDAOALOX15 | |
| SCHEMBL28317487 | 0.71 | HDAC8 (0.41) | ALDH1A1TSHRNAPRTDAOALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059683-A2 | 7-Acylamido-3-cephem-4-carboxylic acids, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-09-08 | — | — | EP | disclosed |