Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290174 | 0.90 | KDM4E (0.36) | CHRM4KDM4EGALR3MEN1KMT2A | |
| SCHEMBL11290131 | 0.89 | KDM4E (0.34) | CHRM4KDM4EGALR3MEN1KMT2A | |
| SCHEMBL11290159 | 0.89 | SMN1; SMN2 (0.36) | CHRM4KDM4EGALR3MEN1KMT2A | |
| SCHEMBL11107034 | 0.87 | PDE5A (0.38) | CHRM4KDM4EGALR3MEN1KMT2A | |
| SCHEMBL10376558 | 0.87 | VDR (0.34) | CHRM4KDM4EMEN1KMT2ABRD4 | |
| SCHEMBL11288029 | 0.87 | KDM4E (0.36) | KDM4EGALR3MEN1KMT2ABRD4 | |
| SCHEMBL10376504 | 0.85 | SMN1; SMN2 (0.38) | CHRM4KDM4EGALR3MEN1KMT2A | |
| SCHEMBL11108006 | 0.85 | MAPT (0.39) | CHRM4KDM4EGALR3MEN1KMT2A | |
| SCHEMBL10378009 | 0.84 | S1PR2 (0.35) | CHRM4KDM4EGALR3MEN1KMT2A | |
| SCHEMBL10378110 | 0.84 | SMN1; SMN2 (0.38) | CHRM4KDM4EGALR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |