Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288709 | 0.83 | SRD5A1 (0.47) | SRD5A1SRD5A2MEN1KMT2ACA12 | |
| SCHEMBL12991922 | 0.81 | SRD5A1 (0.51) | SRD5A1SRD5A2MEN1KMT2ACA12 | |
| SCHEMBL12992249 | 0.78 | MEN1 (0.50) | SRD5A1SRD5A2MEN1KMT2ACA12 | |
| SCHEMBL11277835 | 0.77 | SRD5A1 (0.58) | SRD5A1SRD5A2MEN1KMT2ACA12 | |
| SCHEMBL20178700 | 0.73 | RARA (0.53) | SRD5A1SRD5A2MEN1KMT2ACA12 | |
| SCHEMBL31337627 | 0.71 | SRD5A1 (0.51) | SRD5A1SRD5A2MEN1KMT2ACA12 | |
| SCHEMBL28610379 | 0.71 | SRD5A1 (0.51) | SRD5A1SRD5A2MEN1KMT2ACA12 | |
| SCHEMBL30583360 | 0.71 | SRD5A1 (0.51) | SRD5A1SRD5A2MEN1KMT2ACA12 | |
| SCHEMBL27569997 | 0.71 | MEN1 (0.50) | SRD5A1SRD5A2MEN1KMT2ACA12 | |
| SCHEMBL20119292 | 0.71 | RARA (0.51) | SRD5A1SRD5A2MEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313947-A | TREATMENT OF BLOOD DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4216220-A | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-05 | — | — | US | disclosed |
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |