Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.67 |
| ▸ | MAOA | P21397 | 16/20 | 0.67 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16059342 | 0.93 | MAOB (0.67) | MAOBMAOADRD2 | |
| SCHEMBL11287532 | 0.89 | MAOB (0.67) | MAOBMAOADRD2 | |
| SCHEMBL2842062 | 0.86 | MAOB (0.80) | MAOBMAOADRD2 | |
| SCHEMBL10900191 | 0.83 | MAOB (0.67) | MAOBMAOADRD2 | |
| SCHEMBL18825568 | 0.82 | MAOB (0.70) | MAOBMAOADRD2 | |
| SCHEMBL29487495 | 0.82 | MAOB (0.70) | MAOBMAOADRD2 | |
| SCHEMBL18892577 | 0.82 | MAOB (0.76) | MAOBMAOADRD2 | |
| SCHEMBL6585582 | 0.82 | MAOB (0.67) | MAOBMAOA | |
| SCHEMBL17848639 | 0.82 | MAOB (0.68) | MAOBMAOA | |
| SCHEMBL29923843 | 0.82 | MAOB (0.68) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313947-A | TREATMENT OF BLOOD DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4216220-A | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-05 | — | — | US | disclosed |
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |