SCHEMBL6585582

SCHEMBL6585582

O=C1CCc2ccc(OCCCl)cc2N1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 19/20 0.67
MAOA P21397 17/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1040338 0.94 MAOB (0.70) MAOBMAOA
SCHEMBL238817 0.93 MAOB (0.72) MAOBMAOA
SCHEMBL29545160 0.93 MAOB (0.72) MAOBMAOA
SCHEMBL1038939 0.92 MAOB (0.62) MAOBMAOA
SCHEMBL6588324 0.92 MAOB (0.70) MAOBMAOA
SCHEMBL2842062 0.89 MAOB (0.80) MAOBMAOA
SCHEMBL6583075 0.88 MAOB (0.67) MAOBMAOA
SCHEMBL1207052 0.88 MAOB (0.66) MAOBMAOA
SCHEMBL17848639 0.85 MAOB (0.68) MAOBMAOA
SCHEMBL29923843 0.85 MAOB (0.68) MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101607959-A The dihydroquinoline ketone derivatives, its preparation method and be the pharmaceutical composition of activeconstituents with this compound SHANGHAI INST PHARM INDUSTRY (CN) 2009-12-23 CN disclosed
EP-0957100-B1 DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME KOWA CO (JP) 2004-10-27 EP disclosed
EP-0957100-A1 DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME Kowa Co., Ltd. (JP) 1999-11-17 EP disclosed