Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 8/20 | 0.66 |
| ▸ | ABCC1 | P33527 | 6/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11224541 | 0.90 | ABCB1 (0.54) | ABCB1ABCC1PIK3CAPIK3CGMAPT | |
| SCHEMBL7466534 | 0.89 | ABCB1 (0.64) | ABCB1ABCC1MAPTNPC1KCNMA1 | |
| SCHEMBL2282371 | 0.85 | MAPT (0.68) | ABCB1ABCC1MAPTNPC1NPSR1 | |
| SCHEMBL11222561 | 0.84 | MAPT (0.57) | ABCB1ABCC1MAPTNPC1NPSR1 | |
| SCHEMBL2645986 | 0.84 | ABCB1 (0.66) | ABCB1ABCC1MAPTNPC1NPSR1 | |
| SCHEMBL29530549 | 0.84 | ABCB1 (0.62) | ABCB1ABCC1MAPTNPC1KCNMA1 | |
| SCHEMBL5868784 | 0.84 | ABCB1 (0.62) | ABCB1ABCC1MAPTNPC1KCNMA1 | |
| SCHEMBL1980974 | 0.81 | ABCB1 (0.55) | ABCB1ABCC1MAPTNPC1KMT2A | |
| SCHEMBL10924361 | 0.80 | MAPT (0.50) | ABCB1ABCC1MAPTNPC1NPSR1 | |
| SCHEMBL11277648 | 0.79 | MAPT (0.53) | ABCB1ABCC1MAPTNPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056260-A1 | Pyridinyl-substituted-benz imidazole derivatives and preparation | STERLING DRUG INC. (US) | 1982-07-21 | — | — | EP | disclosed |