SCHEMBL11287688

SCHEMBL11287688

CCCCCCCCCOc1ccc(-c2ccc(C3CCC(CCC)CC3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.48
RAB9A P51151 1/20 0.47
CYP2C9 P11712 2/20 0.47
S1PR3 Q99500 1/20 0.47
NR5A1 Q13285 1/20 0.45
LMNA P02545 2/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
MEN1 O00255 1/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 1/20 0.45
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
LTA4H P09960 1/20 0.43
SPHK1 Q9NYA1 1/20 0.42
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11279047 1.00 RARB (0.48) RARBRAB9ACYP2C9S1PR3NR5A1
SCHEMBL11283580 1.00 RARB (0.48) RARBRAB9ACYP2C9S1PR3NR5A1
SCHEMBL11278181 1.00 RARB (0.48) RARBRAB9ACYP2C9S1PR3NR5A1
SCHEMBL11279779 1.00 RARB (0.48) RARBRAB9ACYP2C9S1PR3NR5A1
SCHEMBL11277065 1.00 RARB (0.48) RARBRAB9ACYP2C9S1PR3NR5A1
SCHEMBL11276839 1.00 RARB (0.48) RARBRAB9ACYP2C9S1PR3NR5A1
SCHEMBL11285601 0.99 RAB9A (0.48) RARBRAB9ACYP2C9S1PR3NR5A1
SCHEMBL11277229 0.96 CYP2C9 (0.50) RARBRAB9ACYP2C9LMNAALDH1A1
SCHEMBL10660536 0.96 CYP2C9 (0.50) RAB9ACYP2C9S1PR3NR5A1LMNA
SCHEMBL10660532 0.96 CYP2C9 (0.50) RAB9ACYP2C9S1PR3NR5A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022183-B1 DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS MERCK PATENT GmbH (DE) 1982-06-23 EP disclosed
US-4330426-A Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-18 US disclosed
EP-0022183-A2 Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements MERCK PATENT GmbH (DE) 1981-01-14 EP disclosed