Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841038 | 0.92 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KMT2AMAPTSLC15A2 | |
| SCHEMBL10841031 | 0.92 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KMT2AMAPTSLC15A2 | |
| SCHEMBL11672426 | 0.91 | HSD17B10 (0.66) | ALDH1A1HSD17B10KMT2AMAPTSLC15A2 | |
| SCHEMBL11672428 | 0.91 | HSD17B10 (0.66) | ALDH1A1HSD17B10KMT2AMAPTSLC15A2 | |
| SCHEMBL11840913 | 0.91 | HSD17B10 (0.66) | ALDH1A1HSD17B10KMT2AMAPTSLC15A2 | |
| SCHEMBL10975191 | 0.91 | ALDH1A1 (0.58) | ALDH1A1HSD17B10KMT2AMAPTSLC15A2 | |
| SCHEMBL10805858 | 0.90 | SCN9A (0.46) | ALDH1A1HSD17B10KMT2AMAPTSLC15A2 | |
| SCHEMBL11584984 | 0.90 | ALDH1A1 (0.45) | ALDH1A1HSD17B10KMT2AMAPTSLC15A2 | |
| SCHEMBL10805852 | 0.90 | SCN9A (0.46) | ALDH1A1HSD17B10KMT2AMAPTSLC15A2 | |
| SCHEMBL11586929 | 0.90 | ALDH1A1 (0.45) | ALDH1A1HSD17B10KMT2AMAPTSLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365062-A | BACTERICIDAL ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1982-12-21 | — | — | US | disclosed |
| US-4307233-A | ANTIBACTERIAL AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |
| US-4307230-A | ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |