Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205684 | 0.92 | LMNA (0.45) | MAPK1ABCB11LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7429435 | 0.91 | TDP1 (0.49) | MAPK1ABCB11LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7433095 | 0.90 | LMNA (0.53) | MAPK1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL11280956 | 0.88 | LMNA (0.51) | MAPK1ABCB11LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7438468 | 0.87 | MAPT (0.50) | MAPK1ABCB11LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7438766 | 0.87 | MAPT (0.54) | MAPK1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL6550151 | 0.87 | GAA (0.56) | MAPK1ABCB11LMNAMAPTTP53 | |
| SCHEMBL6262433 | 0.87 | MAPT (0.68) | MAPK1ABCB11LMNAMAPTMEN1 | |
| SCHEMBL7432301 | 0.87 | LMNA (0.53) | MAPK1ABCB11LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6264573 | 0.87 | LMNA (0.53) | MAPK1ABCB11LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1982000643-A1 | SUBSTITUTED OXIRANECARBONIC ACIDS,PREPARATION AND PHARMACEUTICAL UTILISATION THEREOF | BYK GULDEN LOMBERG CHEM FAB (DE) | 1982-03-04 | — | — | WO | disclosed |