Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29185915 | 0.77 | PARL (0.40) | PARL | |
| SCHEMBL36368 | 0.75 | PARL (0.43) | PARLCA12CA1CA2CA9 | |
| SCHEMBL11835114 | 0.75 | PARL (0.43) | PARLCA12CA1CA2CA9 | |
| SCHEMBL10775869 | 0.75 | PARL (0.43) | PARLCA12CA1CA2CA9 | |
| SCHEMBL7736371 | 0.73 | PARL (0.41) | PARLCA12CA1CA2CA9 | |
| SCHEMBL13158264 | 0.73 | PARL (0.41) | PARLCA12CA1CA2CA9 | |
| SCHEMBL13158284 | 0.73 | PARL (0.41) | PARLCA12CA1CA2CA9 | |
| SCHEMBL5086273 | 0.73 | PARL (0.41) | PARLCA12CA1CA2CA9 | |
| SCHEMBL29748565 | 0.73 | PARL (0.46) | PARLCA12CA1CA2CA9 | |
| SCHEMBL4226221 | 0.73 | PARL (0.41) | PARLCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043341-A | Compositions for degrading trypsin or TMPRSS2 | 国立研究开发法人理化学研究所 | 2023-11-10 | — | — | CN | disclosed |
| US-4364958-A | 1-Substituted-3-cycloalkyl-sulfonyl-pyrrolidine-2,5-dione derivatives and fungicidal compositions thereof | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-12-21 | — | — | US | disclosed |