Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176963 | 0.77 | POLB (0.50) | HSD17B10ALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL13065801 | 0.77 | TSHR (0.54) | HSD17B10ALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL11842789 | 0.77 | HSD17B10 (0.46) | HSD17B10ALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL11660676 | 0.77 | HSD17B10 (0.70) | HSD17B10ALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL13994610 | 0.76 | HTT (0.60) | HSD17B10ALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL28899 | 0.75 | CYP1A2 (0.58) | HSD17B10ALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL4644749 | 0.75 | HTR2A (0.60) | HSD17B10ALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL2152213 | 0.74 | HSD17B10 (0.41) | HSD17B10ALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL11822029 | 0.73 | IDO1 (0.48) | HSD17B10ALDH1A1TDP1CYP2A6TSHR | |
| SCHEMBL331869 | 0.72 | IDO1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001421-B1 | USE OF MERCAPTANS FOR THE HEAT-STABILISATION OF THERMOPLASTIC POLYMERS CONTAINING HALOGEN | CIBA-GEIGY AG (CH) | 1982-06-30 | — | — | EP | claimed |
| EP-0001421-A1 | Use of mercaptans for the heat-stabilisation of thermoplastic polymers containing halogen | CIBA-GEIGY AG (CH) | 1979-04-18 | — | — | EP | claimed |
| EP-0001421-B1 | USE OF MERCAPTANS FOR THE HEAT-STABILISATION OF THERMOPLASTIC POLYMERS CONTAINING HALOGEN | CIBA-GEIGY AG (CH) | 1982-06-30 | — | — | EP | disclosed |
| US-4290942-A | POLYMERCAPTAN, PHOSPHITE, EPOXIDIZED PLASTICIZER | CIBA-GEIGY CORPORATION (US) | 1981-09-22 | — | — | US | disclosed |
| EP-0001421-A1 | Use of mercaptans for the heat-stabilisation of thermoplastic polymers containing halogen | CIBA-GEIGY AG (CH) | 1979-04-18 | — | — | EP | disclosed |