SCHEMBL11289249

SCHEMBL11289249

CC/C=C\C(C)C(=O)C(C)/C=C\CC

nearest known ligand 0.32

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
OXER1 Q8TDS5 4/20 0.32
PPARA Q07869 2/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPT P10636 2/20 0.32
CYP19A1 P11511 2/20 0.32
RXRA P19793 2/20 0.32
PPARG P37231 2/20 0.32
FFAR1 O14842 1/20 0.32
TRPA1 O75762 1/20 0.32
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31
FPR2 P25090 1/20 0.31
F7 P08709 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
F3 P13726 1/20 0.30
PTGS1 P23219 1/20 0.30
KMT2A Q03164 1/20 0.30
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1784274 0.82
SCHEMBL1759158 0.82
SCHEMBL1759157 0.82
SCHEMBL6722495 0.82
SCHEMBL2917720 0.82
SCHEMBL1784273 0.82
SCHEMBL10062292 0.82
SCHEMBL6722499 0.82
SCHEMBL6719031 0.80
SCHEMBL6719039 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4309351-A INTERMEDIATES FOR PROSTAGLANDIN-LIKE COMPOUNDS THE UNIVERSITY OF CHICAGO (US) 1982-01-05 US disclosed