Tubercidin

Tubercidin

SCHEMBL11289302

Nc1ncnc2c1ccn2C1O[C@H](CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADK P55263 3/20 0.82
SLC29A1 Q99808 2/20 0.65
DPP4 P27487 1/20 0.65
MEN1 O00255 1/20 0.65
SLC28A1 O00337 1/20 0.65
MAP3K7 O43318 1/20 0.65
SLC28A2 O43868 1/20 0.65
GAPDH P04406 1/20 0.65
ADORA3 P0DMS8 1/20 0.65
MAPK1 P28482 1/20 0.65
ADORA2A P29274 1/20 0.65
ADORA2B P29275 1/20 0.65
ADORA1 P30542 1/20 0.65
STAT6 P42226 1/20 0.65
PI4KA P42356 1/20 0.65
KMT2A Q03164 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
PI4K2B Q8TCG2 1/20 0.65
DOT1L Q8TEK3 1/20 0.65
PI4K2A Q9BTU6 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tubercidin SCHEMBL8259 1.00 ADK (0.82) ADKSLC29A1DPP4MEN1SLC28A1
Tubercidin SCHEMBL20419149 1.00 ADK (0.82) ADKSLC29A1DPP4MEN1SLC28A1
Tubercidin SCHEMBL6063615 1.00 ADK (0.82) ADKSLC29A1DPP4MEN1SLC28A1
Tubercidin SCHEMBL1739818 1.00 ADK (0.82) ADKSLC29A1DPP4MEN1SLC28A1
Tubercidin SCHEMBL23351430 1.00 ADK (0.82) ADKSLC29A1DPP4MEN1SLC28A1
Tubercidin SCHEMBL23982115 1.00 ADK (0.82) ADKSLC29A1DPP4MEN1SLC28A1
Tubercidin SCHEMBL20418952 1.00 ADK (0.82) ADKSLC29A1DPP4MEN1SLC28A1
Tubercidin SCHEMBL23982350 1.00 ADK (0.82) ADKSLC29A1DPP4MEN1SLC28A1
Tubercidin SCHEMBL20938187 1.00 ADK (0.82) ADKSLC29A1DPP4MEN1SLC28A1
Tubercidin SCHEMBL20419325 1.00 ADK (0.82) ADKSLC29A1DPP4MEN1SLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360166-A1 Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase Merck Sharp & Dohme Corp. (US) 2011-08-24 EP disclosed
EP-0057548-A2 7-Beta-D-arabinofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine 5'-phosphate compounds useful as antiviral agents, pharmaceutical compositions containing the compounds, and processes for producing the compounds WARNER-LAMBERT COMPANY (US) 1982-08-11 EP disclosed