Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275197 | 0.98 | AKR1C1 (0.47) | AKR1C1HDAC4MEN1KMT2ADPP4 | |
| SCHEMBL26135641 | 0.96 | AKR1C1 (0.44) | AKR1C1HDAC4MEN1KMT2ADPP4 | |
| SCHEMBL2572169 | 0.92 | AKR1C1 (0.42) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL6036843 | 0.85 | AKR1C1 (0.52) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL23647372 | 0.84 | OPRM1 (0.47) | AKR1C1OPRM1OPRD1OPRK1 | |
| SCHEMBL9191670 | 0.83 | AKR1C1 (0.50) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL9191673 | 0.83 | AKR1C1 (0.50) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL23762899 | 0.81 | AKR1C1 (0.48) | AKR1C1HDAC4MEN1KMT2AOPRM1 | |
| SCHEMBL4105893 | 0.80 | AKR1C1 (0.47) | AKR1C1HDAC4MEN1KMT2AOPRM1 | |
| SCHEMBL2503374 | 0.80 | AKR1C1 (0.47) | AKR1C1HDAC4MEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4319018-A | IN ACID CATALYST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1982-03-09 | — | — | US | disclosed |