Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170988 | 0.88 | CA12 (0.64) | TP53MAPTCA12CA1CA2 | |
| SCHEMBL7764162 | 0.86 | CA12 (0.65) | CA12CA1CA2CA9LMNA | |
| SCHEMBL19400415 | 0.83 | CA12 (0.61) | CA12CA1CA2CA9LMNA | |
| SCHEMBL28179229 | 0.81 | CA12 (0.59) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL119805 | 0.80 | CA12 (0.67) | CA12CA1CA2CA9LMNA | |
| SCHEMBL23067457 | 0.80 | CA12 (0.58) | CA12CA1CA2CA9LMNA | |
| SCHEMBL28347887 | 0.79 | CA12 (0.61) | TP53MAPTCA12CA1CA2 | |
| SCHEMBL24915804 | 0.79 | SYK (0.51) | TP53MAPTCA12CA1CA2 | |
| SCHEMBL28433159 | 0.79 | CA12 (0.63) | TP53MAPTCA12CA1CA2 | |
| SCHEMBL4649681 | 0.79 | CA12 (0.56) | MAPTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055490-A1 | Tetrahydro-1,2,4-oxadiazin-5-one derivatives, processes for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1982-07-07 | — | — | EP | disclosed |