Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10682952 | 0.83 | CTSL (0.58) | SYKLMNAMEN1KMT2A | |
| SCHEMBL6016839 | 0.81 | SYK (0.57) | SYKSMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL2170988 | 0.81 | CA12 (0.64) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL28327204 | 0.80 | SYK (0.48) | SYKCA12CA1CA2CA9 | |
| SCHEMBL28731412 | 0.80 | IDO1 (0.59) | SYKCA12CA1CA2CA9 | |
| SCHEMBL20570343 | 0.80 | LMNA (0.51) | SYKSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL11289352 | 0.79 | TP53 (0.59) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL22966170 | 0.79 | CA12 (0.58) | SYKCA12CA1CA2CA9 | |
| SCHEMBL716007 | 0.79 | NPC1 (0.56) | SYKCA12CA1NPC1RAB9A | |
| SCHEMBL394244 | 0.79 | ALDH1A1 (0.56) | SYKCA12CA1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |