Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL11296075 | 0.94 | PTPN1 (0.37) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| Methane SCHEMBL11291301 | 0.92 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Methane SCHEMBL11302737 | 0.90 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Methane SCHEMBL11301610 | 0.90 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Methane SCHEMBL11314925 | 0.90 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Methane SCHEMBL11305895 | 0.90 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Methane SCHEMBL11298114 | 0.89 | KDM4E (0.31) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Methane SCHEMBL11306250 | 0.88 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Methane SCHEMBL11290482 | 0.88 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Methane SCHEMBL11352683 | 0.88 | TLR2 (0.32) | ALDH1A1KDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |