Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271958 | 1.00 | MGLL (0.52) | MGLLTSHRHSD17B10ABL1ABCB1 | |
| SCHEMBL3476184 | 1.00 | MGLL (0.52) | MGLLTSHRHSD17B10ABL1ABCB1 | |
| SCHEMBL11278352 | 1.00 | MGLL (0.52) | MGLLTSHRHSD17B10ABL1ABCB1 | |
| SCHEMBL5283982 | 1.00 | MGLL (0.52) | MGLLTSHRHSD17B10ABL1ABCB1 | |
| SCHEMBL11458650 | 1.00 | MGLL (0.52) | MGLLTSHRHSD17B10ABL1ABCB1 | |
| SCHEMBL11247222 | 1.00 | MGLL (0.52) | MGLLTSHRHSD17B10ABL1ABCB1 | |
| SCHEMBL11475163 | 1.00 | MGLL (0.52) | MGLLTSHRHSD17B10ABL1ABCB1 | |
| SCHEMBL11476246 | 1.00 | MGLL (0.52) | MGLLTSHRHSD17B10ABL1ABCB1 | |
| SCHEMBL11465958 | 1.00 | MGLL (0.52) | MGLLTSHRHSD17B10ABL1ABCB1 | |
| SCHEMBL11456707 | 1.00 | MGLL (0.52) | MGLLTSHRHSD17B10ABL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309553-A | HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1982-01-05 | — | — | US | disclosed |
| US-4273785-A | ANTILIPEMIC AGENTS, ANTIATHEROSCEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-06-16 | — | — | US | disclosed |
| US-4216330-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |
| US-4117158-A | ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1978-09-26 | — | — | US | disclosed |