SCHEMBL11289402

SCHEMBL11289402

CCN(c1cccc2ccccc12)C1CC2(CCCC2)Oc2c1ccc(OC)c2OC

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 19/20 0.43
SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11292485 0.90 C5AR1 (0.47) C5AR1SLC6A4
SCHEMBL11475234 0.84 C5AR1 (0.30) C5AR1
SCHEMBL11286697 0.80 C5AR1 (0.40) C5AR1SLC6A4
SCHEMBL11277101 0.79 C5AR1 (0.42) C5AR1
SCHEMBL11275302 0.79 C5AR1 (0.40) C5AR1SLC6A4
SCHEMBL11289304 0.79 C5AR1 (0.44) C5AR1
SCHEMBL11587144 0.79 C5AR1 (0.39) C5AR1
SCHEMBL11276010 0.78 C5AR1 (0.41) C5AR1SLC6A4
SCHEMBL11282317 0.78 C5AR1 (0.51) C5AR1
SCHEMBL11275057 0.77 C5AR1 (0.41) C5AR1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0001428-B1 INSECTICIDAL AND ACARICIDAL AGENTS CONTAINING CHROMAN DERIVATIVES, THEIR PREPARATION AND THEIR USE, AS WELL AS CHROMAN DERIVATIVES AND THEIR PREPARATION BAYER AG (DE) 1982-03-24 EP disclosed
US-4238501-A INSECTICIDES, MITICIDES, PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-12-09 US disclosed
US-4237162-A MITICIDES, LARVACIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-12-02 US disclosed