Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 15/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286697 | 0.99 | C5AR1 (0.40) | C5AR1SLC6A4CYP2D6OPRD1KCNH2 | |
| SCHEMBL11279459 | 0.89 | C5AR1 (0.40) | C5AR1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL11277101 | 0.87 | C5AR1 (0.42) | C5AR1KDM4EALDH1A1MAPT | |
| SCHEMBL11277198 | 0.87 | C5AR1 (0.42) | C5AR1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL11289304 | 0.86 | C5AR1 (0.44) | C5AR1 | |
| SCHEMBL11292485 | 0.83 | C5AR1 (0.47) | C5AR1SLC6A4ALDH1A1 | |
| SCHEMBL11275057 | 0.81 | C5AR1 (0.41) | C5AR1SLC6A4KDM4EALDH1A1GAA | |
| SCHEMBL11472809 | 0.80 | OPRD1 (0.38) | SLC6A4CYP2D6OPRD1KCNH2 | |
| SCHEMBL11275178 | 0.80 | OPRD1 (0.40) | CYP2D6OPRD1KCNH2 | |
| SCHEMBL11276010 | 0.80 | C5AR1 (0.41) | C5AR1SLC6A4KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001428-B1 | INSECTICIDAL AND ACARICIDAL AGENTS CONTAINING CHROMAN DERIVATIVES, THEIR PREPARATION AND THEIR USE, AS WELL AS CHROMAN DERIVATIVES AND THEIR PREPARATION | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4238501-A | INSECTICIDES, MITICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4237162-A | MITICIDES, LARVACIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| EP-0001428-A1 | Insecticidal and acaricidal agents containing chroman derivatives, their preparation and their use, as well as chroman derivatives and their preparation | BAYER AG (DE) | 1979-04-18 | — | — | EP | disclosed |