Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280715 | 0.90 | MAPT (0.38) | SMN1; SMN2HTTLMNANPC1RAB9A | |
| SCHEMBL11285261 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2HTTLMNANPC1RAB9A | |
| SCHEMBL11104840 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTLMNAL3MBTL1NPC1 | |
| SCHEMBL11281476 | 0.86 | S1PR2 (0.39) | SMN1; SMN2HTTL3MBTL1NPC1KMT2A | |
| SCHEMBL11106347 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTLMNAL3MBTL1NPC1 | |
| SCHEMBL11288219 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTLMNAL3MBTL1NPC1 | |
| SCHEMBL11112198 | 0.80 | KDM4E (0.42) | SMN1; SMN2HTTKMT2AHPGDS1PR4 | |
| SCHEMBL11111880 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTLMNAL3MBTL1NPC1 | |
| SCHEMBL11108006 | 0.80 | MAPT (0.39) | SMN1; SMN2HTTLMNANPC1RAB9A | |
| SCHEMBL9221645 | 0.80 | HTR1A (0.41) | SMN1; SMN2HTTLMNAL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |