Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040647 | 0.80 | CYP4F2 (0.36) | ALDH1A1RAB9AKDM4ETSHRNPC1 | |
| SCHEMBL11289513 | 0.74 | ALDH1A1 (0.37) | NPSR1ALDH1A1RAB9AL3MBTL1KDM4E | |
| SCHEMBL11356123 | 0.74 | ALDH1A1 (0.37) | NPSR1ALDH1A1RAB9AL3MBTL1KDM4E | |
| SCHEMBL11357404 | 0.71 | NPSR1 (0.36) | NPSR1ALDH1A1RAB9AL3MBTL1KDM4E | |
| SCHEMBL11357403 | 0.71 | NPSR1 (0.36) | NPSR1ALDH1A1RAB9AL3MBTL1KDM4E | |
| SCHEMBL15482499 | 0.66 | NPSR1 (0.48) | NPSR1ALDH1A1RAB9AL3MBTL1KDM4E | |
| SCHEMBL15482538 | 0.66 | NPSR1 (0.48) | NPSR1ALDH1A1RAB9AL3MBTL1KDM4E | |
| SCHEMBL13468215 | 0.63 | NPSR1 (0.46) | NPSR1ALDH1A1RAB9AL3MBTL1KDM4E | |
| SCHEMBL13468240 | 0.63 | ALDH1A1 (0.47) | NPSR1ALDH1A1RAB9AL3MBTL1TSHR | |
| SCHEMBL5548895 | 0.63 | ALDH1A1 (0.40) | ALDH1A1RAB9AKDM4ETSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021013-B1 | 2,4-DISUBSTITUTED PYRAN DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS PERFUMING AGENTS | BASF Aktiengesellschaft (DE) | 1982-10-13 | — | — | EP | disclosed |
| US-4292244-A | Novel 2,4-disubstituted pyran derivatives, their preparation and their use as scents | BASF AKTIENGESELLSCHAFT (DE) | 1981-09-29 | — | — | US | disclosed |
| EP-0021013-A1 | 2,4-Disubstituted pyran derivatives, their preparation and their application as perfuming agents | BASF Aktiengesellschaft (DE) | 1981-01-07 | — | — | EP | disclosed |