⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364605 | 0.83 | ALDH1A1 (0.31) | — | |
| SCHEMBL31364603 | 0.83 | ALDH1A1 (0.31) | — | |
| SCHEMBL3379483 | 0.79 | — | — | |
| SCHEMBL5452994 | 0.79 | NPC1 (0.34) | — | |
| SCHEMBL119179 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL614543 | 0.78 | TAAR1 (0.47) | — | |
| SCHEMBL17654953 | 0.78 | EPHX2 (0.33) | — | |
| Bromide SCHEMBL1423332 | 0.78 | HRH3 (0.44) | — | |
| Hydrochloric Acid SCHEMBL28055393 | 0.78 | NPC1 (0.33) | — | |
| SCHEMBL2893056 | 0.76 | HRH4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256470-B1 | METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES | DANA FARBER CANCER INST INC (US) | 2023-07-26 | — | — | EP | disclosed |
| US-20210371548-A1 | HYALURONIC ACID DERIVATIVE MODIFIED WITH POLYETHYLENE GLYCOL | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-12-02 | — | — | US | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |
| US-20190142959-A1 | HYALURONIC ACID DERIVATIVES INTO WHICH CATIONIC AND HYDROPHOBIC GROUPS ARE INTRODUCED | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2019-05-16 | — | — | US | disclosed |
| US-10208032-B2 | Benzamide and nicotinamide compounds and methods of using same | ONCOTARTIS INC. (US) | 2019-02-19 | — | — | US | disclosed |
| US-20190031658-A1 | BENZAMIDE AND NICOTINAMIDE COMPOUNDS AND METHODS OF USING SAME | ONCOTARTIS INC. | 2019-01-31 | — | — | US | disclosed |
| US-4358435-A | Ligand compositions and processes for their manufacture and their use in radioimmunoassay | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1982-11-09 | — | — | US | disclosed |