Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289686 | 1.00 | POLB (0.61) | POLBCYP1A2CYP2C19L3MBTL1RECQL | |
| SCHEMBL7900930 | 0.83 | CYP1A2 (0.49) | POLBCYP1A2CYP2C19L3MBTL1HTT | |
| SCHEMBL1186128 | 0.83 | HTT (0.44) | POLBCYP1A2CYP2C19L3MBTL1HTT | |
| SCHEMBL4901313 | 0.83 | CYP1A2 (0.49) | POLBCYP1A2CYP2C19L3MBTL1HTT | |
| SCHEMBL1186125 | 0.83 | HTT (0.44) | POLBCYP1A2CYP2C19L3MBTL1HTT | |
| SCHEMBL4901316 | 0.83 | CYP1A2 (0.49) | POLBCYP1A2CYP2C19L3MBTL1HTT | |
| SCHEMBL425120 | 0.81 | HTT (0.61) | POLBCYP1A2CYP2C19L3MBTL1HTT | |
| SCHEMBL1438908 | 0.81 | RAB9A (0.51) | POLBL3MBTL1RECQLHTTCES2 | |
| SCHEMBL446955 | 0.81 | HTT (0.61) | POLBCYP1A2CYP2C19L3MBTL1HTT | |
| SCHEMBL11290394 | 0.81 | RAB9A (0.51) | POLBL3MBTL1RECQLHTTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051084-A1 | Substituted 1H-1,2,4-triazoles | AMERICAN CYANAMID COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4259504-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-31 | — | — | US | disclosed |