Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.40 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.40 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.40 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283360 | 1.00 | ALOX15 (0.51) | ALOX15TOP2ANPC1RAB9AKMT2A | |
| SCHEMBL11290495 | 1.00 | ALOX15 (0.51) | ALOX15TOP2ANPC1RAB9AKMT2A | |
| SCHEMBL11277018 | 1.00 | ALOX15 (0.51) | ALOX15TOP2ANPC1RAB9AKMT2A | |
| SCHEMBL11284144 | 0.94 | ALOX15 (0.46) | ALOX15TOP2ANPC1RAB9AKMT2A | |
| SCHEMBL11284329 | 0.94 | POLM (0.47) | ALOX15TOP2ANPC1RAB9AKMT2A | |
| SCHEMBL11284260 | 0.92 | POLM (0.44) | ALOX15TOP2ATHRATHRBMGLL | |
| SCHEMBL11284617 | 0.92 | ALOX15 (0.47) | ALOX15TOP2ANPC1RAB9AKMT2A | |
| SCHEMBL11291258 | 0.91 | ALOX15 (0.44) | ALOX15TOP2ATHRATHRBHSD17B3 | |
| Hydrochloric Acid SCHEMBL11283417 | 0.89 | ALOX15 (0.48) | ALOX15RAB9AKMT2A | |
| SCHEMBL11284610 | 0.89 | KMT2A (0.43) | ALOX15TOP2ANPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |