Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287415 | 0.90 | ALOX15 (0.45) | ALOX15KMT2ANPC1RAB9ATOP2A | |
| SCHEMBL11283786 | 0.90 | ALOX15 (0.45) | ALOX15KMT2ANPC1RAB9ATOP2A | |
| SCHEMBL11288388 | 0.90 | ALOX15 (0.45) | ALOX15KMT2ANPC1RAB9ATOP2A | |
| SCHEMBL11290111 | 0.88 | TBXA2R (0.41) | TBXA2RALOX15KMT2AMEN1 | |
| SCHEMBL11277075 | 0.86 | TBXA2R (0.37) | TBXA2RKMT2A | |
| SCHEMBL11283323 | 0.85 | TBXA2R (0.36) | TBXA2RL3MBTL1 | |
| SCHEMBL11290106 | 0.84 | TBXA2R (0.40) | TBXA2RALOX15KMT2ANPC1RAB9A | |
| SCHEMBL11290647 | 0.83 | MAPT (0.38) | TBXA2RKMT2ANPC1RAB9ATDP1 | |
| SCHEMBL11287411 | 0.83 | TBXA2R (0.37) | TBXA2RKMT2A | |
| Alcohol SCHEMBL11559195 | 0.78 | KMT2A (0.39) | KMT2ANPC1RAB9AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |