Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802726 | 0.94 | KDM4E (0.56) | KDM4EGAAALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL8952581 | 0.94 | KDM4E (0.56) | KDM4EGAAALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL8952635 | 0.94 | KDM4E (0.56) | KDM4EGAAALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL4444531 | 0.94 | KDM4E (0.56) | KDM4EGAAALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL8952585 | 0.94 | KDM4E (0.56) | KDM4EGAAALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL19013585 | 0.91 | KDM4E (0.55) | KDM4EGAAALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL6944694 | 0.87 | SMN1; SMN2 (0.56) | GAAALDH1A1SMN1; SMN2CYP2C9L3MBTL1 | |
| SCHEMBL8459209 | 0.85 | GAA (0.48) | KDM4EGAAALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL7745866 | 0.85 | SMN1; SMN2 (0.49) | KDM4EGAAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL515834 | 0.84 | KDM4E (0.54) | KDM4EGAAALDH1A1SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044927-A1 | Alkylamino-desoxy-1,4;3,6-dianhydro-hexite-nitrate substituted by purine bases, process for their preparation and their pharmaceutical compositions | Dr. Willmar Schwabe GmbH & Co. (DE) | 1982-02-03 | — | — | EP | disclosed |