Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419575 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL1822005 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL11290176 | 0.85 | KDM4E (0.59) | SMN1; SMN2KDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9116970 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL10394883 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9394689 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL6885101 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9395064 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL6944694 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MAPK1HSD17B10HPGD | |
| SCHEMBL8952581 | 0.82 | KDM4E (0.56) | SMN1; SMN2KDM4EALDH1A1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998014181-A1 | TREATMENT AND PREVENTION OF HEPATIC DISORDERS | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-09 | — | — | WO | claimed |
| WO-2001021166-A1 | TREATMENT AND PREVENTION OF HEPATIC DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-03-29 | — | — | WO | disclosed |
| US-5922757-A | ADMINISTERING ALPHA-TOCOPHEROL TO PATIENTS WITH HEPATITIS C WHO ARE REFRACTORY TO INTERFERON | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-07-13 | — | — | US | disclosed |
| WO-1998014181-A1 | TREATMENT AND PREVENTION OF HEPATIC DISORDERS | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-09 | — | — | WO | disclosed |