Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281881 | 0.91 | CTNNB1 (0.45) | MAPK14CTNNB1WNT3ATTRMAPK1 | |
| Hydrochloric Acid SCHEMBL10896191 | 0.90 | CTNNB1 (0.44) | MAPK14CTNNB1WNT3ATTRMAPK1 | |
| SCHEMBL11278709 | 0.88 | TBXA2R (0.43) | MAPK14EZH2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL11281678 | 0.86 | TBXA2R (0.42) | CTNNB1WNT3AMAPK1ALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL11282114 | 0.86 | NOTUM (0.39) | MAPK14LPAR1LPAR5L3MBTL1KMT2A | |
| SCHEMBL11420355 | 0.84 | MAPK14 (0.41) | MAPK14CTNNB1WNT3ATTRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11289624 | 0.83 | TOP1 (0.43) | MAPK14L3MBTL1TDP1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL11290079 | 0.82 | RAB9A (0.41) | CTNNB1WNT3AMAPK1ALDH1A1LMNA | |
| SCHEMBL11284277 | 0.82 | TTR (0.45) | CTNNB1WNT3ATTRMAPK1ALDH1A1 | |
| SCHEMBL11284807 | 0.81 | KMT2A (0.40) | MAPK14TTRL3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |