SCHEMBL11290229

SCHEMBL11290229

O=C(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
LMNA P02545 1/20 0.35
CA2 P00918 10/20 0.34
CA1 P00915 9/20 0.34
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
GAA P10253 1/20 0.32
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2787061 1.00 THRB (0.59) THRBLMNACA2CA1MMP1
SCHEMBL11280493 1.00 THRB (0.59) THRBLMNACA2CA1MMP1
SCHEMBL3956302 1.00 THRB (0.59) THRBLMNACA2CA1MMP1
SCHEMBL31425787 1.00 THRB (0.59) THRBLMNACA2CA1MMP1
SCHEMBL31425789 1.00 THRB (0.59) THRBLMNACA2CA1MMP1
SCHEMBL2019285 0.97 THRB (0.55) THRBLMNACA2CA1MMP1
SCHEMBL28733002 0.94 THRB (0.52) THRBCA2CA1MMP1MMP2
Lithium SCHEMBL30701478 0.94 THRB (0.52) THRBCA2CA1MMP1MMP2
Methane SCHEMBL29283765 0.94 THRB (0.52) THRBCA2CA1MMP1MMP2
SCHEMBL29175472 0.94 THRB (0.52) THRBCA2CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11292763-B2 Methods of making a polyfluorinated allyl ether and compounds relating to the methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US disclosed
EP-3896052-A1 METHODS OF MAKING A POLYFLUORINATED ALLYL ETHER AND COMPOUNDS RELATING TO THE METHODS 3M Innovative Properties Co. (US) 2021-10-20 EP disclosed
EP-3625201-B1 METHODS OF MAKING A POLYFLUORINATED ALLYL ETHER AND COMPOUNDS RELATING TO THE METHODS 3M INNOVATIVE PROPERTIES CO (US) 2021-09-29 EP disclosed
EP-3625201-A2 METHODS OF MAKING A POLYFLUORINATED ALLYL ETHER AND COMPOUNDS RELATING TO THE METHODS 3M Innovative Properties Company (US) 2020-03-25 EP disclosed
WO-2018211457-A2 METHODS OF MAKING A POLYFLUORINATED ALLYL ETHER AND COMPOUNDS RELATING TO THE METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-11-22 WO disclosed
US-4349650-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-14 US disclosed
US-4292449-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
US-4275225-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-23 US disclosed
US-4273729-A CARBONYL OR SULFONYL FLUORIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed
US-4273728-A NITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed