SCHEMBL11290263

SCHEMBL11290263

CC(C)([C]=O)C1CCCCCN1C=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11298179 1.00 MEN1 (0.33) MEN1KMT2A
SCHEMBL25939290 0.77 MEN1 (0.36) MEN1KMT2A
SCHEMBL12572277 0.74 MEN1 (0.32) MEN1KMT2A
SCHEMBL11294394 0.73
SCHEMBL4772645 0.72 MEN1 (0.38) MEN1KMT2A
SCHEMBL28584990 0.66 NAMPT (0.33) MEN1KMT2A
SCHEMBL4780196 0.66 NAMPT (0.33) MEN1KMT2A
SCHEMBL25939278 0.65
SCHEMBL23143621 0.65
SCHEMBL12224195 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4345071-A AZIDOALKYL-HETEROCYCLIC AMIDINE INTERMEDIATES LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) 1982-08-17 US disclosed
EP-0049683-A2 Imidazo-rifamycines, process for their preparation, pharmaceutical preparations containing them and their use CIBA-GEIGY AG (CH) 1982-04-14 EP disclosed
US-4229443-A Derivatives of penicillanic acid LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) 1980-10-21 US disclosed