Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28584990 | 0.94 | NAMPT (0.33) | MEN1KMT2A | |
| SCHEMBL4780196 | 0.94 | NAMPT (0.33) | MEN1KMT2A | |
| SCHEMBL28917591 | 0.94 | NAMPT (0.33) | MEN1KMT2A | |
| SCHEMBL28643104 | 0.85 | — | — | |
| SCHEMBL12572277 | 0.72 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL11290263 | 0.72 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL11298179 | 0.72 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL4028303 | 0.71 | — | — | |
| SCHEMBL4772640 | 0.71 | NAMPT (0.37) | — | |
| SCHEMBL21057424 | 0.68 | VNN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| CN-107531679-A | Aromatic amides analog derivative, its preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |