Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.66 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431130 | 0.87 | TDP1 (0.55) | EGFRNR4A2ALDH1A1GAAMAPT | |
| SCHEMBL6811215 | 0.87 | EGFR (0.68) | EGFRNR4A1NR4A2NR4A3MAOB | |
| SCHEMBL8843719 | 0.87 | NPC1 (0.70) | EGFRMAOBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6811506 | 0.84 | EGFR (0.69) | EGFRNR4A1NR4A2NR4A3MAOB | |
| SCHEMBL1630447 | 0.84 | NR4A1 (0.68) | EGFRNR4A1NR4A2NR4A3MAOB | |
| SCHEMBL958582 | 0.84 | EGFR (0.69) | EGFRNR4A1NR4A2NR4A3MAOB | |
| SCHEMBL1557011 | 0.84 | FFAR1 (0.71) | EGFRNR4A1NR4A2NR4A3MAOB | |
| SCHEMBL4152328 | 0.83 | EGFR (0.72) | EGFRNR4A1NR4A2NR4A3MAOB | |
| SCHEMBL27517502 | 0.83 | EGFR (0.68) | EGFRNR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6283205 | 0.82 | EGFR (0.70) | EGFRNR4A1NR4A2NR4A3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |