Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.68 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962776 | 0.87 | MAOB (0.52) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL9787125 | 0.87 | PLA2G4B (0.67) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL657234 | 0.86 | TDP1 (0.55) | RAB9ASMN1; SMN2MAPK1NPC1ALDH1A1 | |
| SCHEMBL10797162 | 0.86 | MAOB (0.67) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL9653413 | 0.86 | NPC1 (0.65) | MAOBRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL8081324 | 0.86 | NR4A2 (0.57) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL9047885 | 0.86 | NR4A1 (0.57) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL6899078 | 0.84 | NR4A1 (0.56) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL11290489 | 0.84 | EGFR (0.66) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL6893992 | 0.83 | NR4A1 (0.55) | NR4A1NR4A2NR4A3MAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020883-B | 3-cyano-2-aminopyridine derivative and preparation method and application thereof | 广西民族大学 | 2022-02-08 | — | — | CN | claimed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | claimed |
| US-12227472-B2 | Series of skin-whitening (lightening) compounds | UNIGEN, INC. (US) | 2025-02-18 | — | — | US | disclosed |
| US-20230399282-A1 | Series of Skin-Whitening (Lightening) Compounds | UNIGEN, INC. (US) | 2023-12-14 | — | — | US | disclosed |
| US-11739040-B2 | Series of skin-whitening (lightening) compounds | UNIGEN, INC. (US) | 2023-08-29 | — | — | US | disclosed |
| EP-4046619-A1 | SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS | Unigen, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |
| CN-109020883-B | 3-cyano-2-aminopyridine derivative and preparation method and application thereof | 广西民族大学 | 2022-02-08 | — | — | CN | disclosed |
| EP-3542780-B1 | SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS | UNIGEN INC (US) | 2022-01-19 | — | — | EP | disclosed |
| US-20210188751-A1 | Series of Skin-Whitening (Lightening) Compounds | UNIGEN, INC. (US) | 2021-06-24 | — | — | US | disclosed |
| US-10941098-B2 | Series of skin whitening (lightening) compounds | UNIGEN, INC. (US) | 2021-03-09 | — | — | US | disclosed |
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |
| WO-1992012981-A1 | SUBSTITUTED PHENYL-1,3 DIOXOLOQUINOLINE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | GLAXO INC. (US) | 1992-08-06 | — | — | WO | disclosed |
| EP-0496634-A1 | Substituted phenyl-1,3-dioxoloquinoline derivatives and their use as antitumor agents | GLAXO INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5126351-A | Inhibitors of topoisomerase | GLAXO INC. (US) | 1992-06-30 | — | — | US | disclosed |
| US-3952021-A | α-(3,4-Dimethoxyphenethylaminomethyl)-3,4 or 3,5-dihydroxybenzylalcohols and salts thereof | TANABE SEIYAKU CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739040-B2 | Series of skin-whitening (lightening) compounds | TYR, TH, MAOB | NR4A1 2772/4885NR4A2 1977/4885NR4A3 2134/4885 |
| US-20230399282-A1 | Series of Skin-Whitening (Lightening) Compounds | TYR, TH, MAOB | NR4A1 2772/4885NR4A2 1977/4885NR4A3 2134/4885 |
| US-10941098-B2 | Series of skin whitening (lightening) compounds | TYR, MAOB, TH | NR4A1 2962/4885NR4A2 2178/4885NR4A3 2251/4885 |
| US-20210188751-A1 | Series of Skin-Whitening (Lightening) Compounds | TYR, TH, MAOB | NR4A1 2772/4885NR4A2 1977/4885NR4A3 2134/4885 |
| US-12227472-B2 | Series of skin-whitening (lightening) compounds | TYR, TH, MAOB | NR4A1 2772/4885NR4A2 1977/4885NR4A3 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.