Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301103 | 0.94 | HAO1 (0.49) | ELANEPKMGAAHAO1L3MBTL1 | |
| SCHEMBL11298069 | 0.94 | HAO1 (0.49) | ELANEPKMGAAHAO1L3MBTL1 | |
| SCHEMBL11300267 | 0.94 | HAO1 (0.49) | ELANEPKMGAAHAO1L3MBTL1 | |
| SCHEMBL11301118 | 0.87 | ELANE (0.45) | ELANEPKMGAAHAO1L3MBTL1 | |
| SCHEMBL11294429 | 0.87 | HAO1 (0.47) | ELANEPKMGAAHAO1L3MBTL1 | |
| SCHEMBL11295025 | 0.86 | HTT (0.51) | ELANEGAAHAO1L3MBTL1LMNA | |
| SCHEMBL11296575 | 0.86 | HTT (0.51) | ELANEGAAHAO1L3MBTL1LMNA | |
| SCHEMBL11294471 | 0.86 | HTT (0.51) | ELANEGAAHAO1L3MBTL1LMNA | |
| SCHEMBL11300297 | 0.85 | ELANE (0.43) | ELANEPKMGAAHAO1L3MBTL1 | |
| SCHEMBL11294436 | 0.85 | GAA (0.47) | ELANEPKMGAAL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | disclosed |