Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 5/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301103 | 1.00 | HAO1 (0.49) | HAO1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL11298069 | 1.00 | HAO1 (0.49) | HAO1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL11290553 | 0.94 | ELANE (0.51) | HAO1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL11295025 | 0.92 | HTT (0.51) | HAO1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL11296575 | 0.92 | HTT (0.51) | HAO1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL11294471 | 0.92 | HTT (0.51) | HAO1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL11292210 | 0.89 | HAO1 (0.49) | HAO1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL11295671 | 0.89 | HAO1 (0.49) | HAO1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL11299857 | 0.89 | HAO1 (0.49) | HAO1L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL11296740 | 0.88 | HAO1 (0.48) | HAO1L3MBTL1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | disclosed |