Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288323 | 0.87 | ALDH1A1 (0.55) | ALDH1A1GAAPOLBHDAC1HDAC6 | |
| SCHEMBL11289748 | 0.86 | ALDH1A1 (0.54) | ALDH1A1GAAPOLBHDAC1HDAC6 | |
| SCHEMBL11292942 | 0.86 | ALDH1A1 (0.54) | ALDH1A1GAAPOLBHDAC1HDAC6 | |
| SCHEMBL11292746 | 0.85 | ALDH1A1 (0.56) | ALDH1A1GAAPOLBHDAC1HDAC6 | |
| SCHEMBL13879503 | 0.83 | ALDH1A1 (0.77) | ALDH1A1GAAPOLBHDAC1HDAC6 | |
| SCHEMBL11270312 | 0.83 | GAA (0.74) | ALDH1A1GAAPOLBHDAC1HDAC6 | |
| SCHEMBL13668088 | 0.80 | KMT2A (0.57) | ALDH1A1GAAPOLBHDAC1HDAC6 | |
| SCHEMBL13670497 | 0.80 | KMT2A (0.57) | ALDH1A1GAAPOLBHDAC1HDAC6 | |
| SCHEMBL29721615 | 0.78 | HDAC1 (0.58) | ALDH1A1GAAPOLBHDAC1HDAC6 | |
| SCHEMBL13793062 | 0.77 | ALDH1A1 (0.54) | ALDH1A1GAAPOLBHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060610-A1 | Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents | PFIZER INC. (US) | 1982-09-22 | — | — | EP | disclosed |