Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 11/20 | 0.71 |
| ▸ | CACNA1D | Q01668 | 11/20 | 0.71 |
| ▸ | CACNA1S | Q13698 | 11/20 | 0.71 |
| ▸ | CACNA1C | Q13936 | 11/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | THPO | P40225 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10964416 | 0.97 | CACNA1F (0.75) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10965655 | 0.97 | CACNA1F (0.72) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL7379893 | 0.95 | CACNA1F (0.78) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10963501 | 0.93 | CACNA1F (0.66) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10964237 | 0.93 | CACNA1F (0.70) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10963856 | 0.91 | CACNA1C (0.63) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL7439297 | 0.90 | CACNA1F (0.72) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11829739 | 0.90 | CACNA1F (0.88) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| Niludipine SCHEMBL691639 | 0.90 | CACNA1F (0.84) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11298568 | 0.89 | CACNA1C (0.80) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063359-A1 | 1,4-Dihydropyridine derivatives and processes for preparing the same | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-10-27 | — | — | EP | claimed |