Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.33 |
| ▸ | F2 | P00734 | 5/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394084 | 0.77 | CYP19A1 (0.44) | CYP19A1 | |
| SCHEMBL1619410 | 0.75 | — | — | |
| SCHEMBL20624767 | 0.75 | — | — | |
| SCHEMBL20624836 | 0.75 | — | — | |
| SCHEMBL24299728 | 0.73 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL10192292 | 0.73 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL18981114 | 0.71 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL18981060 | 0.71 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL17147749 | 0.71 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL303670 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051557-A1 | 5-Cyano-prostacycline derivatives, their preparation and their use in medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-05-12 | — | — | EP | disclosed |