SCHEMBL1129138

SCHEMBL1129138

Cc1cc(Cc2ccccc2)cc(C(=O)O)c1O

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 2/20 0.83
CXCL12 P48061 2/20 0.83
PTPN1 P18031 8/20 0.69
PTPN2 P17706 3/20 0.69
PTPN6 P29350 3/20 0.69
HNF4A P41235 1/20 0.58
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
ACMSD Q8TDX5 1/20 0.48
KLKB1 P03952 1/20 0.47
CTSB P07858 1/20 0.47
MMP9 P14780 1/20 0.47
DNMT1 P26358 1/20 0.47
DNMT3B Q9UBC3 1/20 0.47
DNMT3L Q9UJW3 1/20 0.47
DNMT3A Q9Y6K1 1/20 0.47
LDHA P00338 1/20 0.47
LDHB P07195 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29688181 1.00 HMGB1 (0.83) HMGB1CXCL12PTPN1PTPN2PTPN6
SCHEMBL9755153 0.91 HMGB1 (1.00) HMGB1CXCL12PTPN1PTPN2PTPN6
SCHEMBL6369577 0.87 HMGB1 (0.73) HMGB1CXCL12PTPN1PTPN2PTPN6
SCHEMBL9480008 0.84 HMGB1 (0.55) HMGB1CXCL12PTPN1PTPN2PTPN6
SCHEMBL27609813 0.82 PTPN1 (0.62) HMGB1CXCL12PTPN1PTPN2PTPN6
SCHEMBL17262506 0.82 HMGB1 (0.56) HMGB1CXCL12PTPN1PTPN2PTPN6
SCHEMBL5444611 0.81 PTPN1 (1.00) HMGB1CXCL12PTPN1PTPN2PTPN6
SCHEMBL29236440 0.80 PTPN1 (0.97) HMGB1CXCL12PTPN1PTPN2PTPN6
SCHEMBL9652211 0.80 PTPN1 (0.63) HMGB1CXCL12PTPN1PTPN2PTPN6
SCHEMBL28346820 0.80 HMGB1 (0.53) HMGB1CXCL12PTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5017398-A None JP disclosed
EP-4022391-B1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2026-03-04 EP disclosed
EP-3636446-B1 RECORDING MATERIAL, RECORDING SHEET AND USE OF A COMPOUND AS COLOUR-DEVELOPING AGENT NIPPON SODA CO (JP) 2025-04-16 EP disclosed
CN-114667279-B Thermosensitive recording material containing non-phenolic color developer 索理思科技开曼公司 2025-03-25 CN disclosed
US-12151497-B2 Heat sensitive recording material with non-phenolic color developers SOLENIS TECHNOLOGIES, L.P. (US) 2024-11-26 US disclosed
US-11529819-B2 Recording material and compound NIPPON SODA CO., LTD. (JP) 2022-12-20 US disclosed
EP-4022391-A2 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS Solenis Technologies Cayman, L.P. (KY) 2022-07-06 EP disclosed
CN-114667279-A Heat-sensitive recording material containing non-phenol color developer 索理思科技开曼公司 2022-06-24 CN disclosed
CN-110709255-B Recording material and compound 日本曹达株式会社 2021-08-06 CN disclosed
WO-2021041600-A2 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS SOLENIS TECHNOLOGIES CAYMAN, L.P. (KY) 2021-03-04 WO disclosed
EP-0155593-A2 Fluoran compounds and recording sheets containing them KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1985-09-25 EP disclosed
US-4536220-A PHOTOSTABILITY, DISCOLORATION INHIBITION KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1985-08-20 US disclosed
US-4524373-A Fluoran derivatives as new compounds, process for preparing the same and recording system utilizing the same as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1985-06-18 US disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
EP-0112710-A1 Fluoran derivatives KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-07-04 EP disclosed
EP-0089752-A2 Fluoran derivatives, process for their preparation and their use in recording systems KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1983-09-28 EP disclosed
US-4403051-A NONVISCOUS MIXTURE OF POLYVINYL ALCOHOL AND PULP KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) 1983-09-06 US disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed
US-4199619-A REACTION ON BASE SHEET BETWEEN COLOR FORMER IN FORM OF MICROENCAPSULATED OILY CORE MATERIAL AND ORGANIC ACCEPTOR COATED WITH CAROBXYLIC LATEX ON BASE SHEET KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1980-04-22 US disclosed
US-3983292-A Pressure sensitive recording papers SANKO CHEMICAL COMPANY LTD. (JA) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11529819-B2 Recording material and compound H1-0, DOT1L, H1-4 HMGB1 1102/4885CXCL12 1960/4885PTPN1 855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.