Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.83 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.83 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.69 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.69 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.69 |
| ▸ | HNF4A | P41235 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.47 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | LDHB | P07195 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129138 | 1.00 | HMGB1 (0.83) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL9755153 | 0.91 | HMGB1 (1.00) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL6369577 | 0.87 | HMGB1 (0.73) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL9480008 | 0.84 | HMGB1 (0.55) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL27609813 | 0.82 | PTPN1 (0.62) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL17262506 | 0.82 | HMGB1 (0.56) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL5444611 | 0.81 | PTPN1 (1.00) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL29236440 | 0.80 | PTPN1 (0.97) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL9652211 | 0.80 | PTPN1 (0.63) | HMGB1CXCL12PTPN1PTPN2PTPN6 | |
| SCHEMBL28346820 | 0.80 | HMGB1 (0.53) | HMGB1CXCL12PTPN1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4022391-A2 | HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS | Solenis Technologies Cayman, L.P. (KY) | 2022-07-06 | — | — | EP | disclosed |