Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 16/20 | 0.67 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.67 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291682 | 1.00 | ACE (0.67) | ACEACE2KLK5 | |
| SCHEMBL10976266 | 0.92 | ACE (0.78) | ACEACE2 | |
| SCHEMBL11283912 | 0.92 | ACE (0.78) | ACEACE2 | |
| SCHEMBL11122197 | 0.89 | ACE (0.84) | ACEACE2 | |
| SCHEMBL11122199 | 0.89 | ACE (0.84) | ACEACE2 | |
| SCHEMBL11283726 | 0.85 | ACE (0.68) | ACEACE2KLK5 | |
| SCHEMBL11283744 | 0.85 | ACE (0.68) | ACEACE2KLK5 | |
| SCHEMBL11121798 | 0.83 | ACE (0.70) | ACEACE2KLK5 | |
| SCHEMBL11121801 | 0.83 | ACE (0.70) | ACEACE2KLK5 | |
| SCHEMBL11122705 | 0.82 | ACE (0.59) | ACEACE2KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053017-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | disclosed |