SCHEMBL11291920

SCHEMBL11291920

Oc1c(Cl)cc(Cl)cc1Cl.[KH]

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.93
TSHR P16473 7/20 0.93
ALDH1A1 P00352 4/20 0.93
CYP3A4 P08684 2/20 0.93
RECQL P46063 2/20 0.93
TTR P02766 3/20 0.61
HPGD P15428 4/20 0.59
THRB P10828 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
ALOX15 P16050 2/20 0.59
ALOX12 P18054 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
HIF1A Q16665 2/20 0.59
MAPK1 P28482 2/20 0.59
CASP1 P29466 2/20 0.59
KDM4E B2RXH2 1/20 0.59
SLC22A2 O15244 1/20 0.59
SLC22A1 O15245 1/20 0.59
NR1I2 O75469 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28024617 0.97 HSD17B10 (0.88) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL184648 0.97 HSD17B10 (1.00) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL8872103 0.97 HSD17B10 (1.00) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL29827111 0.93 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL28244966 0.93 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL2808115 0.93 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL20380030 0.93 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
Methyl Alcohol SCHEMBL28184301 0.90 HSD17B10 (0.88) HSD17B10TSHRALDH1A1CYP3A4RECQL
Bicarbonate SCHEMBL5147009 0.85 HSD17B10 (0.78) HSD17B10TSHRALDH1A1CYP3A4RECQL
Bicarbonate SCHEMBL19514733 0.85 HSD17B10 (0.78) HSD17B10TSHRALDH1A1CYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101883485-A Enhanced retention through a process comprising surface treatment of functional particulate support materials and functional particulate support materials made therefrom WORLD MINERALS INC 2010-11-10 CN disclosed
US-4347377-A Process for the preparation of polyhalogenphenyl carbamates CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1982-08-31 US disclosed