SCHEMBL2808115

SCHEMBL2808115

Oc1c(Cl)cc(Cl)cc1Cl.[NaH]

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.93
TSHR P16473 7/20 0.93
ALDH1A1 P00352 4/20 0.93
CYP3A4 P08684 2/20 0.93
RECQL P46063 2/20 0.93
TTR P02766 3/20 0.61
HPGD P15428 4/20 0.59
THRB P10828 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
ALOX15 P16050 2/20 0.59
ALOX12 P18054 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
HIF1A Q16665 2/20 0.59
MAPK1 P28482 2/20 0.59
CASP1 P29466 2/20 0.59
KDM4E B2RXH2 1/20 0.59
SLC22A2 O15244 1/20 0.59
SLC22A1 O15245 1/20 0.59
NR1I2 O75469 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28024617 0.97 HSD17B10 (0.88) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL184648 0.97 HSD17B10 (1.00) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL8872103 0.97 HSD17B10 (1.00) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL29827111 0.93 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL11291920 0.93 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL20380030 0.93 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL28244966 0.93 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
Methyl Alcohol SCHEMBL28184301 0.90 HSD17B10 (0.88) HSD17B10TSHRALDH1A1CYP3A4RECQL
Bicarbonate SCHEMBL19514733 0.85 HSD17B10 (0.78) HSD17B10TSHRALDH1A1CYP3A4RECQL
Bicarbonate SCHEMBL5147009 0.85 HSD17B10 (0.78) HSD17B10TSHRALDH1A1CYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233771-A Process for continuously synthesizing prochloraz and intermediate acylate of prochloraz raw material 江西汇和化工有限公司 2020-06-05 CN claimed
CN-100340550-C Method for preparing prochloraz SOUTH CHINA NORMAL UNIVERSTIY (CN) 2007-10-03 CN claimed
CN-1763014-A Method for preparing prochloraz SOUTH CHINA NORMAL UNIVERSTIY (CN) 2006-04-26 CN claimed
CN-117050018-A Process for continuously synthesizing prochloraz and intermediate acylate of prochloraz raw material 盐城师范学院 2023-11-14 CN disclosed
CN-115850181-A Method for synthesizing prochloraz 江西汇和化工有限公司 2023-03-28 CN disclosed
CN-107688065-B Gas chromatography-mass spectrometry combined detection method for chloromethyl methyl ether residue in bulk drug 上海药明康德新药开发有限公司 2020-08-14 CN disclosed
CN-111233771-A Process for continuously synthesizing prochloraz and intermediate acylate of prochloraz raw material 江西汇和化工有限公司 2020-06-05 CN disclosed
EP-2207416-B1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM IMERYS FILTRATION MINERALS INC (US) 2018-11-07 EP disclosed
CN-104888401-A Method for dechlorination from chlorophenol pollutant by using alkali metal zinc borate compound via photocatalysis XINJIANG TECH INST PHYSICS CAS 2015-09-09 CN disclosed
US-20100239679-A1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM WORLD MINERALS, INC. (US) 2010-09-23 US disclosed
EP-2207416-A1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM World Minerals, Inc. (US) 2010-07-21 EP disclosed
WO-2009045941-A1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM WORLD MINERALS, INC. (US) 2009-04-09 WO disclosed
US-7514139-B2 A fiber, sheet or textile of a polyurethane formed from an anionic bis(hydroxy(oxy)alkyl) di- or oligoester prepared from a dicarboxylic acid containing one or two sulfonate, sulfate or sulfamate groups (e.g., 5-sulfoisophthalic acid); moisture-absorbing/releasing properties and dyeability SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2009-04-07 US disclosed
CN-100340550-C Method for preparing prochloraz SOUTH CHINA NORMAL UNIVERSTIY (CN) 2007-10-03 CN disclosed
US-20060182922-A1 Polyol component for polyurethane formation comprising anionic diol and composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-17 US disclosed
CN-1763014-A Method for preparing prochloraz SOUTH CHINA NORMAL UNIVERSTIY (CN) 2006-04-26 CN disclosed