Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.61 |
| ▸ | RAF1 | P04049 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288616 | 0.87 | ERN1 (0.52) | MAPTMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL11289066 | 0.86 | TTR (0.52) | MAPTMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL11294315 | 0.82 | VCAM1 (0.55) | MAPTMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL11306670 | 0.80 | TTR (0.57) | MAPTMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL7659900 | 0.80 | MAOB (0.56) | MAPTMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL11294652 | 0.79 | MAPK1 (0.49) | MAPTMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL11294900 | 0.79 | MAPT (0.57) | MAPTMAPK1ALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL11288014 | 0.77 | MAPT (0.56) | MAPTMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL7659895 | 0.77 | MAOB (0.56) | MAPTMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL2310798 | 0.76 | TDP1 (0.48) | MAPTMAPK1ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |