Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656787 | 0.82 | HPGD (0.57) | MAPTHPGDRAB9ALMNANPSR1 | |
| SCHEMBL5260478 | 0.78 | MAPT (0.52) | MAPTHPGDRAB9ALMNANPSR1 | |
| SCHEMBL103890 | 0.78 | KMT2A (0.70) | MAPTHPGDRAB9ALMNANPSR1 | |
| SCHEMBL6617827 | 0.78 | MAPT (0.61) | MAPTHPGDRAB9ALMNANPSR1 | |
| SCHEMBL8506170 | 0.76 | MAPT (0.59) | MAPTHPGDRAB9ALMNANPSR1 | |
| SCHEMBL1906677 | 0.76 | ALOX15 (0.61) | MAPTHPGDRAB9ALMNANPSR1 | |
| SCHEMBL22505175 | 0.74 | MAPT (0.57) | MAPTHPGDRAB9ALMNANPSR1 | |
| SCHEMBL4458942 | 0.74 | MAPT (0.57) | MAPTHPGDRAB9ALMNANPSR1 | |
| SCHEMBL5790248 | 0.73 | GAA (0.62) | MAPTHPGDRAB9ALMNANPSR1 | |
| SCHEMBL943227 | 0.73 | GAA (0.62) | MAPTHPGDRAB9ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056319-A2 | Substituted pyrimidin-2-ones and the salts thereof | NYEGAARD & CO. A/S (NO) | 1982-07-21 | — | — | EP | disclosed |